Determination of Risk Factors for the Development of Diabetic Foot Disease

Author :  

Year-Number: 2021-2
Yayımlanma Tarihi: 2021-08-31 19:05:24.0
Language : İngilizce
Konu : Family Physician
Number of pages: 47-56
Mendeley EndNote Alıntı Yap

Abstract

Keywords

Abstract

Aim: The aim of this study was to analyze risk factors involved in the development of diabetic foot disease.
Methods: Eighty-five diabetic foot patients and 109 diabetes mellitus diagnosed patients without diabetic foot disease (as the control group) were involved in this study. This was an analytic, case-control study. A questionnaire interrogating the patients’ socio-demographic characteristics, general information about their diseases and Morisky Medication Adherence Scale-8 were used in this research.
Results: According to this study, diabetic foot disease is more frequently observed in male patients, in smokers, in those with an education level lower than high school and in those with a low income level. The rate of insulin users was higher in the group with diabetic foot disease. A history of retinopathy has been identified as a risk factor for diabetic foot disease. Each 1 unit of decline in e-GFR level increases the risk of diabetic foot development by 2%. Regular exercise is five times protective against diabetic foot disease.
Conclusions: A decline in e-GFR values was a risk for diabetic foot disease; regular blood glucose monitoring and regular exercise were protective against diabetic foot disease. These factors should be considered in the management of diabetes mellitus.

Keywords


  • 1. Abbas ZG. Reducing diabetic limb amputations in developing countries. Expert review of endocrinology & metabolism. 2015; 10(4): 425-434.

  • 2. Katsilambros N, Dounis E, Makrilakis K, Tentolouris N, Tsapogas, P. Atlas of the diabetic foot. John Wiley & Sons. 2010.

  • 3. Vinik AI, Erbas T, Cassellini CM. Diabetic cardiac autonomic neuropathy, inflammation and cardiovascular disease. Journal of diabetes investigation. 2013; 4(1): 4-18.

  • 4. Noor S, Zubair M, Ahmad J. Diabetic foot ulcer—a review on pathophysiology, classification and microbial etiology. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2015; 9(3): 192-199.

  • 5. Bissonnette JM. Adherence: a concept analysis. Journal of advanced nursing. 2008; 63(6): 634-643.

  • 6. Jimmy B, Jose J. Patient medication adherence: measures in daily practice. Oman medical journal. 2011; 26(3): 155.

  • 7. Brown MT, Bussell JK. Medication adherence: WHO cares?. In: Mayo clinic proceedings. Elsevier, 2011; 304-314.

  • 8. Neiman AB, Ruppar T, Ho M, et al.. CDC grand rounds: improving medication adherence for chronic disease management—innovations and opportunities. MMWR. Morbidity and mortality weekly report. 2017; 66(45), 1248.

  • 9. Dima AL, Allemann SS, Dunbar‐Jacob J, Hughes DA, Vrijens B, Wilson IB. TEOS: A framework for constructing operational definitions of medication adherence based on Timelines–Events–Objectives– Sources. British Journal of Clinical Pharmacology. 2021; 87(6), 2521-2533.

  • 10. Ocakoglu G, Demirci H, GUCLU OA, Guclu Y. Association between health literacy and medication adherence in the elderly population with chronic disease. Ethiopian Journal of Health Development. 2020; 34(2).

  • 11. Esen I, Demirci H, Guclu M, Esen SA, Simsek EE. The Relationship Between Health Literacy, Diabetic Control, and Disease-Specific Complications in Patients with Type 1 Diabetes Mellitus. Southern Clinics of Istanbul Eurasia. 2018; 29(3).

  • 12. Polonsky WH, Henry RR. Poor medication adherence in type 2 diabetes: recognizing the scope of the problem and its key contributors. Patient preference and adherence. 2016; 10: 1299.

  • 13. Conn VS, Ruppar TM. Medication adherence outcomes of 771 intervention trials: systematic review and metaanalysis. Preventive medicine. 2017; 99: 269-276.

  • 14. Dwajani S, Prabhu MR, Ranjana G, Sahajananda H. Importance of medication adherence and factors affecting it. IP International Journal of Comprehensive and Advanced Pharmacology. 2020; 3(2), 69-77.

  • Journal of Nursing Practice. 2021; e12950.

  • 26. Cinar Y, Demirci H, Satman I. Principles of Exercise and Its Role in the Management of Diabetes Mellitus. Diabetes Mellıtus–Insights and Perspectives. 2013; 149.

  • 27. Fernando DJS, Hutchison A, Veves A, Gokal R, Boulton AJM. Risk factors for non‐ischaemic foot ulceration in diabetic nephropathy. Diabetic medicine. 1991; 8(3): 223-225.

  • 28. Babaliche P, Nadpara RA, Maldar A. Association between estimated glomerular filtration rate and microvascular complications in type II diabetes mellitus patients: a 1-year cross-sectional study. Journal of the National Medical Association. 2019; 111(1): 83-87.

  • 29. McIntosh C, MacGilchrist C. The association between declining kidney function and diabetic foot disease. The Diabetic Foot Journal. 2018; 21(2).

                                                                                                                                                                                                        
  • Article Statistics